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 Timeline



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 1910 Instituto Central de Análisis Clínicos
 1943 Medicine for transfusion: lyophilized plasma from a single donor
 1951 Development of plasmapheresis. Blood bank activities and manufacture of IV solutions commence.
 1957 Gri-Cel: manufacture of medical instruments.
 1966 Cell-Washer centrifuge.
 1972 The new production facilities move from Barcelona to Parets del Vallès. Industrial plasma fractionation. Beginning of cryoprecipitate production.
 1980 Marketing of FVIII concentrate
 1984 Production of virally inactivated FVIII concentrate.
 1986 Prothrombin Concentrate Complex
 1991 Foundation of Biomat.
 1992 Marketing of lyophilized IVIG.
 1994 Marketing of Pasteurized Liquid IVIG and Fanhdi® double inactivated FVII/VWF High Purity.
 1994 Marketing of blood bags.
 1995 Launching of Diana® System.
 1995 Obtaining the Establishment License and the product license for albumin granted by the American Food & Drug Administration (FDA).
 1997 Viral Inactivation Service of Transfusional Plasma (MB-VIP)
 1998 Launching of WADiana®
 1999 Launching of Triturus® and Soyacal®
 2000 Marketing of Leucored® (Blood Bags with Online filter)
 2004 Launch of high purity double inactivated factor IX concentrate.
Launch of DG Gel® and Grifill® 3.0
ISO 14001 certification obtained.
 2005 Anbinex®, antithrombin III concentrate, marketed.
Launch of Grifols Partnership, a manufacturing service for sterile solutions to third parties.
Fleboflex®, polypropylene bags for intravenous solutions.
Tauramin marketed, amino acid solution for clinical nutrition.
 2006 FDA licence obtained for Flebogamma® DIF IGIV and for the new IGIV manufacturing plant in Barcelona.
 2007 FDA approval of Alphanate® to treat VWD.
EMEA grants license for Flebogammadif®.
Launch of the new hemostasis autoanalyzer.
 2008 Obtained the new FDA license for the new coagulation factor sterile dosage activity in the plasma derivatives plant in Los Angeles.

Grifols began marketing its PediGri® On Line information system in the US. This product allows healthcare professionals to accurately trace the plasma used in all of Grifols’ plasma derivatives, from the time of donation to the manufacture of the end product.

Grifols obtains licensing for its intravenous immunoglobulin, Flebogamma® 5% DIF, in Australia.

  
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