Livesaving plasma

Plasma, the liquid part of blood, contains proteins and other components of incalculable therapeutic value. From plasma, Grifols develops medicines to treat patients around the world living with chronic, rare, prevalent and, at times, life-threatening diseases.

Patient Centricity

The patients we serve around the world are able to lead better lives. Patients inspire the work we do every day.

 

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Our Bioscience division has the largest network of plasma donation centers in the world and markets plasma-derived medicines, as well as other innovative treatments with applications in various fields of medicine.

Plasma therapies and other innovative solutions

HEMATOLOGY

  • Factor VIII/von Willebrand factor and factor IX are clotting factors indicated in the treatment of hemophilia A and von Willebrand's disease, as well as hemophilia B, which are genetic deficiencies that prevent the blood from clotting properly.
  • Another plasma protein involved in the blood clotting process, antithrombin III, is indicated in the treatment of hereditary antithrombin deficiency. Research is also currently underway in COVID-19 and trauma.
  • Fostamatinib, a spleen tyrosine kinase (SYK) inhibitor, is indicated in chronic immune thrombocytopenia, a disorder in which the immune system attacks and destroys platelets.
  • Immunoglobulin (IgG) is indicated to treat immune thrombocytopenia.
  • The combination of the plasma protein fibrinogen with the enzyme thrombin acts as a biological sealant in the control of surgical bleeding.

 

HEPATOLOGY / INTENSIVE CARE

  • Albumin is used to restore circulatory volume and protein loss in pathophysiological conditions such as liver cirrhosis, cardiocirculatory failure, trauma or severe burns. Its use as a treatment for decompensated liver cirrhosis with ascites, acute-on-chronic liver failure, hepatic encephalopathy and sepsis is currently under investigation.

IMMUNOLOGY / INFECTIOUS DISEASES

  • Immunoglobulin (IgG) is indicated to treat primary immunodeficiencies, in which the immune system is diminished or impaired and the body does not have the ability to fight infections.
  • Specific hyperimmune immunoglobulins are used to provide immediate immune protection after exposure to possible infections such as rabies, tetanus, hepatitis A or hepatitis B, as well as to treat Rh incompatibility.

 

PULMONOLOGY

  • Alpha-1 proteinase inhibitor is a plasma protein that prevents certain enzymes from attacking healthy lung tissue. It is used to treat alpha-1 antitrypsin deficiency, a genetic disease also known as alpha-1, which is a major cause of chronic obstructive pulmonary disease (COPD).

 

NEUROLOGY

  • Immunoglobulin (IgG) is indicated for the treatment of chronic inflammatory demyelinating polyneuropathy, a rare autoimmune neurological disease in which the immune system attacks and damages the protective coating covering the nerves, causing weakness, pain, numbness, and tingling in the arms and legs, as well as loss of balance that may impair the ability to walk.
  • Plasma exchange with albumin is being investigated for the treatment of Alzheimer's disease, the most common form of dementia.