Expanding our infectious disease treatments
Grifols has invested in treatments for infectious diseases, including hepatitis B virus (HBV), rabies, Zika virus and Ebola.1
Our Biotest group is also working on a breakthrough plasma protein, trimodulin, a unique polyvalent Ig product including IgG, IgA as well as IgM, to reduce dysregulated immune responses in patients with severe pneumonia. A Phase 3 clinical trial is focused on severe community-acquired pneumonia (sCAP), one of the leading causes of death worldwide,2 in patients with high inflammatory markers. A second Phase 3 trial is focusing on a specific subgroup of hospitalized COVID-19 patients with early systemic inflammation.
The company is also working on a potential treatment for human cytomegalovirus (CMV) infection during pregnancy to prevent prenatal transmission from the mother to her unborn child, using Cytotect®, a plasma-derived polyclonal Ig preparation (CMVIg) containing large amounts of anti-CMV antibodies.